UBE2MP1

Across TCGA patient cohorts, UBE2MP1 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2MP1-associated genes across cancer lineages are ASNS, JNK_pT183_Y185, and VHL. Each is linked with UBE2MP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2MP1-to-partner and partner-to-UBE2MP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by UBE2MP1-low versus UBE2MP1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2MP1→partner) and Y-score (partner→UBE2MP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	ASNS →	+0.501	+3.009	.030	.019	3	2
UCEC	JNK_pT183_Y185 →	-0.179	-2.000	.010	.030	3	2
UCEC	VHL →	-1.144	-2.321	<.001	.006	3	2
UCEC	ATM →	-0.750	-3.000	<.001	.001	3	2
LUAD	Beclin →	-0.129	-2.321	.040	.035	3	1
UCEC	eEF2 →	+0.400	+3.321	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

ASNS by UBE2MP1 expression — LUSC

Explore this box plot interactively →