UBE2L5

Across TCGA pan-cancer cohorts, UBE2L5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated UBE2L5 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher UBE2L5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UBE2L5 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and GBM are the cancer types where UBE2L5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	II,III,IV	0.527	0.335	.017	5	view →
HNSC	DFS	Median	II,III,IV	0.973	0.896	.025	4	view →
GBM	DFS	Quartile	All	0.299	0.521	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

UBE2L5–PDAC (DFS)

Open the PDAC breakdown →