Across TCGA patient cohorts, UBE2L3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,248 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible UBE2L3-associated genes across cancer lineages are RTCB, NDUFA6, and MAPK1. Each is linked with UBE2L3 in more than 5 cancer types. Because this analysis shows association rather than direction, both UBE2L3-to-partner and partner-to-UBE2L3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2L3→partner) and Y-score (partner→UBE2L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RTCB →	+0.483	+0.441	<.001	<.001	3	6
UCEC	NDUFA6 →	+0.659	+0.391	<.001	<.001	3	5
LSCC	MAPK1 →	+0.463	+0.234	<.001	<.001	3	4
GBM	TXN2 →	+0.389	+0.261	<.001	.004	3	4
LSCC	PHF5A →	+0.453	+0.244	<.001	<.001	3	4
LSCC	DRG1 →	+0.472	+0.318	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,248 associations by consensus.

Exploration

UBE2L3 survival (RNA) · tumor vs normal (RNA) · all UBE2L3 data types