Across TCGA patient cohorts, UBE2L3 mutation is significantly associated with the RNA expression of many other genes, with 1,892 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2L3-associated genes across cancer lineages are MIR511, RPL31P40, and COX6A1P3. Each is linked with UBE2L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2L3-to-partner and partner-to-UBE2L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2L3→partner) and Y-score (partner→UBE2L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR511 →	+0.561	+7.485	<.001	<.001	3	2
SKCM	RPL31P40 →	+0.135	+5.513	<.001	.004	3	1
HNSC	COX6A1P3 →	+0.161	+5.368	<.001	.005	3	1
HNSC	RNU6ATAC29P →	+0.450	+5.182	<.001	.007	3	1
BLCA	RNU6-1273P →	+0.373	+7.640	<.001	.009	3	1
BLCA	SNORD115-22 →	+0.448	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,892 associations by consensus.

Exploration

UBE2L3 survival (RNA) · tumor vs normal (RNA) · all UBE2L3 data types