UBE2J2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBE2J2 mutation is significantly associated with the RNA expression of many other genes, with 1,072 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2J2-associated genes across cancer lineages are SPACA7, NEUROD6, and RNU6-1122P. Each is linked with UBE2J2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2J2-to-partner and partner-to-UBE2J2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPACA7 grouped by UBE2J2-low versus UBE2J2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2J2→partner) and Y-score (partner→UBE2J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCSPACA7 →+0.036+4.409.009.00632
CESCNEUROD6 →+0.015+4.812.002.00632
CESCRNU6-1122P →+0.213+4.969<.001.00432
CESCSNORD56B →+0.599+4.760<.001.00332
UCECRPS29P32 →+0.460+2.336<.001.00632
BRCARNU5A-2P →+0.306+6.112<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,072 associations by consensus.

SPACA7 by UBE2J2 expression — CESC

Box plot of SPACA7 in UBE2J2-low vs UBE2J2-high samples in CESC.

Explore this box plot interactively →

Exploration