UBE2J2

Across TCGA patient cohorts, UBE2J2 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2J2-associated genes across cancer lineages are INPP4B, 14-3-3_beta, and FoxM1. Each is linked with UBE2J2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2J2-to-partner and partner-to-UBE2J2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by UBE2J2-low versus UBE2J2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2J2→partner) and Y-score (partner→UBE2J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.486	-3.321	.001	.010	3	2
UCEC	14-3-3_beta →	-0.117	-2.973	.016	.035	3	1
UCEC	FoxM1 →	+0.372	+2.999	.002	.035	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.430	+2.459	.037	.020	3	1
UCEC	ACVRL1 →	-0.174	-2.459	.008	.020	3	1
UCEC	JNK_pT183_Y185 →	-0.198	-3.000	.015	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

INPP4B by UBE2J2 expression — UCEC

Explore this box plot interactively →