UBE2J2

Across TCGA cell cohorts, UBE2J2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,009 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2J2-associated GO terms across cancer lineages are Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, Regulation of telomerase RNA localization to Cajal body, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with UBE2J2 in more than 14 cancer types. Because this analysis shows association rather than direction, both UBE2J2-to-partner and partner-to-UBE2J2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by UBE2J2-low versus UBE2J2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2J2→partner) and Y-score (partner→UBE2J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.139	+0.642	<.001	<.001	3	15
PANCREAS	Regulation of telomerase RNA localization to Cajal body →	+0.118	+0.742	<.001	<.001	3	15
BONE	Microtubule cytoskeleton organization involved in mitosis →	+0.114	+0.827	<.001	<.001	3	14
STOMACH	Cellular response to methionine →	+0.124	+0.777	<.001	<.001	3	14
BONE	RISC complex assembly →	+0.137	+0.850	<.001	<.001	3	14
BONE	Regulation of DNA-templated DNA replication →	+0.131	+0.883	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,009 associations by consensus.

Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I by UBE2J2 expression — BONE

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