UBE2J1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBE2J1 mutation is significantly associated with the RNA expression of many other genes, with 2,577 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2J1-associated genes across cancer lineages are TRIM43CP, MTND4LP19, and RNU6-1213P. Each is linked with UBE2J1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2J1-to-partner and partner-to-UBE2J1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2J1→partner) and Y-score (partner→UBE2J1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTRIM43CP →+0.166+1.872.001.00132
BLCAMTND4LP19 →+0.195+5.289<.001.00332
UCECRNU6-1213P →+0.213+3.555<.001<.00132
UCECSETP7 →+0.079+1.697.005.00632
BLCANPM1P4 →+0.076+4.533<.001.00532
UCECPOM121C →+0.455+2.375<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,577 associations by consensus.

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