Across TCGA pan-cancer cohorts, UBE2H Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated UBE2H data layer compared with 24 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher UBE2H Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBE2H expression acts as an unfavorable survival marker.

LGG are the cancer types where UBE2H Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.185	0.832	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: UBE2H tumor-vs-normal RNA expression · all UBE2H data types