UBE2F-SCLY

Across TCGA pan-cancer cohorts, UBE2F-SCLY RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated UBE2F-SCLY data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher UBE2F-SCLY RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBE2F-SCLY expression acts as an unfavorable survival marker, although some lineages such as BRCA and SARC show a favorable association.

KIRC, KICH, and OV are the cancer types where UBE2F-SCLY RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.515	0.720	.002	97	view →
KICH	OS	Quartile	II,III,IV	0.491	1.000	.001	83	view →
OV	OS	Median	All	0.791	0.886	<.001	50	view →
ACC	OS	Median	All	0.402	0.944	<.001	48	view →
LUSC	OS	Tertile	III,IV	0.177	0.555	<.001	44	view →
LGG	DFS	Median	All	0.781	0.877	<.001	26	view →
LIHC	OS	Median	III,IV	0.421	0.731	.001	18	view →
THCA	OS	Tertile	II,III,IV	0.896	0.979	.013	16	view →
KIRP	DFS	Median	II,III,IV	0.245	0.674	<.001	14	view →
DLBC	OS	Tertile	All	0.769	1.000	.010	11	view →
LUAD	DFS	Median	All	0.757	0.820	.028	8	view →
CHOL	DFS	Tertile	III,IV	0.154	0.529	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

UBE2F-SCLY–KIRC (DFS)

Open the KIRC breakdown →