UBE2E3

Across TCGA cell cohorts, UBE2E3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,176 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible UBE2E3-associated GO terms across cancer lineages are Positive regulation of mitotic cell cycle, Cell division, and Positive regulation of cell cycle phase transition. Each is linked with UBE2E3 in more than 13 cancer types. Because this analysis shows association rather than direction, both UBE2E3-to-partner and partner-to-UBE2E3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cell cycle grouped by UBE2E3-low versus UBE2E3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2E3→partner) and Y-score (partner→UBE2E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of mitotic cell cycle →	+0.091	+1.561	<.001	<.001	3	13
BLOOD_Myeloma	Cell division →	+0.045	+1.570	.002	<.001	2	14
BREAST	Positive regulation of cell cycle phase transition →	+0.080	+1.494	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic cell cycle phase transition →	+0.089	+1.064	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cell cycle phase transition →	+0.107	+0.925	<.001	.002	3	11
BREAST	Positive regulation of cell cycle →	+0.064	+1.395	.004	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,176 associations by consensus.

Positive regulation of mitotic cell cycle by UBE2E3 expression — BREAST

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