UBE2E2

Across TCGA pan-cancer cohorts, UBE2E2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated UBE2E2 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher UBE2E2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBE2E2 expression acts as an unfavorable survival marker.

COAD, LSCC, and CCRCC are the cancer types where UBE2E2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.805	1.000	.015	36	view →
LSCC	OS	Quartile	All	0.700	0.959	<.001	10	view →
CCRCC	OS	Median	All	0.906	1.000	.016	10	view →
GBM	DFS	Median	All	0.286	0.436	.026	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

UBE2E2–COAD (DFS)

Open the COAD breakdown →