UBE2E2

Across TCGA cell cohorts, UBE2E2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,976 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UBE2E2-associated GO terms across cancer lineages are Protein monoubiquitination, Protein K11-linked ubiquitination, and Maintenance of location in cell. Each is linked with UBE2E2 in more than 9 cancer types. Because this analysis shows association rather than direction, both UBE2E2-to-partner and partner-to-UBE2E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein monoubiquitination grouped by UBE2E2-low versus UBE2E2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2E2→partner) and Y-score (partner→UBE2E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein monoubiquitination →	+0.077	+1.204	<.001	.002	3	9
BREAST	Protein K11-linked ubiquitination →	+0.085	+1.580	.001	<.001	3	9
SOFT_TISSUE	Maintenance of location in cell →	+0.081	+2.086	<.001	<.001	3	9
STOMACH	Positive regulation of protein modification by small protein conjugation or removal →	+0.075	+2.582	.002	.002	2	10
SOFT_TISSUE	Positive regulation of protein ubiquitination →	+0.049	+1.804	.007	<.001	3	9
BONE	Relaxation of smooth muscle →	-0.242	-2.113	<.001	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,976 associations by consensus.

Protein monoubiquitination by UBE2E2 expression — BREAST

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