UBE2E2

Across TCGA cell cohorts, UBE2E2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2E2-associated genes across cancer lineages are UGT2B10, HS3ST6, and LCE1C. Each is linked with UBE2E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2E2-to-partner and partner-to-UBE2E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B10 grouped by UBE2E2-low versus UBE2E2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2E2→partner) and Y-score (partner→UBE2E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	UGT2B10 →	+0.055	+4.922	<.001	.009	3	1
BLOOD_Leukemia	HS3ST6 →	+0.019	+5.539	<.001	.003	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	GAGE12H →	+0.978	+4.922	<.001	.009	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1
BLOOD_Leukemia	SPATA31A3 →	+0.035	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

UGT2B10 by UBE2E2 expression — BLOOD_Leukemia

Explore this box plot interactively →