Across TCGA pan-cancer cohorts, UBE2E1-AS1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated UBE2E1-AS1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher UBE2E1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBE2E1-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and UCS show a favorable association.

LIHC, COAD, and KICH are the cancer types where UBE2E1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Quartile	All	0.166	0.324	<.001	79	view →
COAD	DFS	Tertile	II,III,IV	0.675	0.799	.002	65	view →
KICH	OS	Median	II,III,IV	0.654	0.960	.006	39	view →
BLCA	OS	Tertile	III,IV	0.421	0.683	.008	29	view →
ACC	DFS	Quartile	II,III,IV	0.116	0.693	<.001	28	view →
OV	OS	Median	All	0.882	0.799	.013	26	view →
UCS	OS	Median	II,III,IV	0.770	0.428	.004	24	view →
UCEC	DFS	Median	All	0.793	0.881	.002	24	view →
KIRP	DFS	Quartile	All	1.000	0.579	.008	21	view →
CHOL	DFS	Quartile	II,III,IV	0.480	0.119	.007	18	view →
KIRC	DFS	Median	II,III,IV	0.452	0.636	.015	15	view →
PAAD	OS	Quartile	All	0.630	0.325	.016	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

Exploration

Same gene, other analysis: UBE2E1-AS1 tumor-vs-normal RNA expression · all UBE2E1-AS1 data types