UBE2D2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBE2D2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,763 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible UBE2D2-associated genes across cancer lineages are LARP6, IFT52, and APMAP. Each is linked with UBE2D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2D2-to-partner and partner-to-UBE2D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2D2 versus LARP6 in BRCA, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D2→partner) and Y-score (partner→UBE2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCALARP6 →-0.664-0.435<.001<.00132
COADIFT52 →-0.462-1.006.003<.00131
COADAPMAP →-0.797-0.934.002<.00131
COADRAB40AL →+0.087+0.872.006.00131
COADGIPR →+0.727+1.047.002<.00131
COADGOLGA8UP →+0.202+0.772<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,763 associations by consensus.

UBE2D2 vs LARP6 — BRCA

Per-sample scatter of UBE2D2 vs LARP6 in BRCA (Pearson r = -0.29).

Explore this scatter interactively →

Exploration