UBE2D2

Across TCGA cell cohorts, UBE2D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,305 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2D2-associated GO terms across cancer lineages are Negative regulation of metaphase/anaphase transition of cell cycle, Negative regulation of chromosome separation, and Dihydrofolate metabolic process. Each is linked with UBE2D2 in more than 10 cancer types. Because this analysis shows association rather than direction, both UBE2D2-to-partner and partner-to-UBE2D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of metaphase/anaphase transition of cell cycle grouped by UBE2D2-low versus UBE2D2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2D2→partner) and Y-score (partner→UBE2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.132	+0.731	<.001	.003	3	11
LIVER	Negative regulation of chromosome separation →	+0.132	+0.731	<.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Dihydrofolate metabolic process →	+0.198	+0.789	.003	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.110	+0.898	<.001	<.001	3	10
BREAST	Immunoglobulin V(D)J recombination →	+0.120	+0.671	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic nuclear division →	+0.126	+0.762	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,305 associations by consensus.

Negative regulation of metaphase/anaphase transition of cell cycle by UBE2D2 expression — LIVER

Explore this box plot interactively →