UBE2B

Across TCGA patient cohorts, UBE2B protein abundance is significantly associated with the RNA expression of many other genes, with 13,888 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBE2B-associated genes across cancer lineages are HSPA4, HINT1, and FHL1. Each is linked with UBE2B in more than 3 cancer types. Because this analysis shows association rather than direction, both UBE2B-to-partner and partner-to-UBE2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2B versus HSPA4 in LUAD, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2B→partner) and Y-score (partner→UBE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HSPA4 →	+0.329	+0.168	.002	.001	3	4
LUAD	HINT1 →	+0.391	+0.214	<.001	<.001	3	3
UCEC	FHL1 →	+0.929	+0.231	.007	.001	3	2
UCEC	RNU6-1146P →	-0.467	-0.184	.008	.007	3	2
GBM	FAM13B →	+0.367	+0.223	<.001	.001	3	2
GBM	PSMA1 →	+0.604	+0.243	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,888 associations by consensus.

UBE2B vs HSPA4 — LUAD

Explore this scatter interactively →