UBE2B

Across TCGA cell cohorts, UBE2B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,880 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UBE2B-associated GO terms across cancer lineages are Regulation of protein ubiquitination, Vesicle fusion with Golgi apparatus, and Dendritic transport of messenger ribonucleoprotein complex. Each is linked with UBE2B in more than 10 cancer types. Because this analysis shows association rather than direction, both UBE2B-to-partner and partner-to-UBE2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein ubiquitination grouped by UBE2B-low versus UBE2B-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2B→partner) and Y-score (partner→UBE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of protein ubiquitination →	+0.051	+0.728	<.001	.001	3	11
OVARY	Vesicle fusion with Golgi apparatus →	+0.106	+0.592	<.001	<.001	3	11
BONE	Dendritic transport of messenger ribonucleoprotein complex →	-0.073	-0.924	<.001	<.001	3	10
SOFT_TISSUE	Regulation of protein modification by small protein conjugation or removal →	+0.040	+0.464	.007	.008	2	11
BONE	Negative regulation of lysosome organization →	+0.120	+0.984	.001	<.001	3	9
STOMACH	Regulation of centriole elongation →	+0.080	+0.888	.009	.005	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,880 associations by consensus.

Regulation of protein ubiquitination by UBE2B expression — BLOOD_Lymphoma

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