UBE2A

Across TCGA cell cohorts, UBE2A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,353 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2A-associated GO terms across cancer lineages are Amino acid metabolic process, Regulation of protein modification by small protein conjugation or removal, and Establishment of mitotic sister chromatid cohesion. Each is linked with UBE2A in more than 11 cancer types. Because this analysis shows association rather than direction, both UBE2A-to-partner and partner-to-UBE2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amino acid metabolic process grouped by UBE2A-low versus UBE2A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2A→partner) and Y-score (partner→UBE2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Amino acid metabolic process →	-0.083	-1.396	<.001	<.001	3	12
KIDNEY	Regulation of protein modification by small protein conjugation or removal →	+0.055	+0.572	<.001	<.001	3	12
OVARY	Establishment of mitotic sister chromatid cohesion →	+0.109	+0.587	.001	.005	3	11
LUNG_SCLC	Regulation of miRNA-mediated gene silencing →	+0.134	+0.728	<.001	<.001	3	11
LIVER	Cytosolic ciliogenesis →	+0.152	+1.272	<.001	.001	3	11
LUNG_SCLC	Regulation of post-transcriptional gene silencing by regulatory ncRNA →	+0.134	+0.728	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,353 associations by consensus.

Amino acid metabolic process by UBE2A expression — LIVER

Explore this box plot interactively →