Across TCGA patient cohorts, UBD RNA expression is significantly associated with the protein abundance of many other proteins, with 8,536 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible UBD-associated proteins across cancer lineages are GBP4, STAT1, and PSMB10. Each is linked with UBD in more than 7 cancer types. Because this analysis shows association rather than direction, both UBD-to-partner and partner-to-UBD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBD→partner) and Y-score (partner→UBD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GBP4 →	+0.648	+0.138	<.001	<.001	3	8
CCRCC	STAT1 →	+0.656	+0.325	<.001	<.001	3	7
HNSC	PSMB10 →	+0.451	+0.174	<.001	.001	3	7
BRCA	PSMB9 →	+0.403	+0.151	<.001	<.001	3	7
HNSC	CD74 →	+0.677	+0.260	<.001	<.001	3	6
HNSC	GBP1 →	+0.870	+0.168	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,536 associations by consensus.

Exploration

UBD survival (RNA) · tumor vs normal (RNA) · all UBD data types