Across TCGA patient cohorts, UBD protein abundance is significantly associated with the RNA expression of many other genes, with 3,318 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible UBD-associated genes across cancer lineages are NSMCE1, DALRD3, and OR2I1P. Each is linked with UBD in more than 2 cancer types. Because this analysis shows association rather than direction, both UBD-to-partner and partner-to-UBD results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBD→partner) and Y-score (partner→UBD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NSMCE1 →	-1.075	-1.097	<.001	<.001	3	3
BRCA	DALRD3 →	-1.070	-1.215	<.001	<.001	3	3
BRCA	OR2I1P →	+2.493	+1.142	<.001	.002	3	3
BRCA	SEC22C →	-0.430	-0.679	<.001	.002	3	3
BRCA	PXMP4 →	-1.284	-0.863	.002	.005	3	2
BRCA	BLVRA →	-0.905	-0.779	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,318 associations by consensus.

Exploration

UBD survival (RNA) · tumor vs normal (RNA) · all UBD data types