Across TCGA cell cohorts, UBD RNA expression is significantly associated with the go_rna of many other GO terms, with 2,531 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBD-associated GO terms across cancer lineages are Spermatid differentiation, Antigen processing and presentation of peptide antigen via MHC class I, and Regulation of type III interferon production. Each is linked with UBD in more than 11 cancer types. Because this analysis shows association rather than direction, both UBD-to-partner and partner-to-UBD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBD→partner) and Y-score (partner→UBD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Spermatid differentiation →	-0.025	-1.921	<.001	.002	3	12
BREAST	Antigen processing and presentation of peptide antigen via MHC class I →	+0.163	+1.268	.004	.006	2	12
BREAST	Regulation of type III interferon production →	+1.104	+1.239	<.001	.005	3	11
LIVER	Basement membrane disassembly →	+1.549	+4.143	<.001	<.001	2	12
URINARY_TRACT	Cellular response to tumor necrosis factor →	+0.088	+2.444	.003	.009	3	11
LARGE_INTESTINE	Spermatid development →	-0.027	-2.015	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,531 associations by consensus.

Exploration

UBD survival (RNA) · tumor vs normal (RNA) · all UBD data types