UBC

Across TCGA patient cohorts, UBC RNA expression is significantly associated with the protein abundance of many other proteins, with 9,993 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBC-associated proteins across cancer lineages are TOP2B_S1552, PPP1R13L_S567, and RALB. Each is linked with UBC in more than 5 cancer types. Because this analysis shows association rather than direction, both UBC-to-partner and partner-to-UBC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBC versus TOP2B_S1552 in UCEC, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBC→partner) and Y-score (partner→UBC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOP2B_S1552 →	-0.434	-0.944	.002	.004	2	6
PDAC	PPP1R13L_S567 →	+0.542	+0.373	<.001	<.001	3	4
LSCC	RALB →	+0.355	+0.285	<.001	<.001	3	4
PDAC	FOSL2_S200 →	+0.387	+0.280	.005	.009	3	4
LSCC	KIAA1671_S1019 →	+0.707	+0.268	<.001	<.001	3	4
UCEC	STX7 →	-0.307	-1.137	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,993 associations by consensus.

UBC vs TOP2B_S1552 — UCEC

Explore this scatter interactively →