UBBP4

Across TCGA patient cohorts, UBBP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,057 significant associations in total. THCA shows the largest number of these associations.

The most reproducible UBBP4-associated GO terms across cancer lineages are Mitochondrial proton-transporting ATP synthase complex assembly, Protein insertion into ER membrane by stop-transfer membrane-anchor sequence, and Tail-anchored membrane protein insertion into ER membrane. Each is linked with UBBP4 in more than 16 cancer types. Because this analysis shows association rather than direction, both UBBP4-to-partner and partner-to-UBBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial proton-transporting ATP synthase complex assembly grouped by UBBP4-low versus UBBP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBBP4→partner) and Y-score (partner→UBBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial proton-transporting ATP synthase complex assembly →	+0.037	+0.355	<.001	<.001	3	16
MESO	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.043	+0.488	<.001	<.001	3	16
UCS	Tail-anchored membrane protein insertion into ER membrane →	+0.045	+1.402	.007	<.001	1	17
TGCT	Mitochondrial translation →	+0.040	+0.809	<.001	<.001	3	15
CESC	Proton-transporting two-sector ATPase complex assembly →	+0.041	+0.560	<.001	<.001	3	14
ACC	Ribosomal small subunit export from nucleus →	+0.035	+0.743	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,057 associations by consensus.

Mitochondrial proton-transporting ATP synthase complex assembly by UBBP4 expression — STAD

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