UBBP4

Across TCGA cell cohorts, UBBP4 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible UBBP4-associated genes across cancer lineages are OR14A2, GRIFIN, and OR10K1. Each is linked with UBBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBBP4-to-partner and partner-to-UBBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR14A2 grouped by UBBP4-low versus UBBP4-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBBP4→partner) and Y-score (partner→UBBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR14A2 →	+0.035	+5.169	<.001	.005	3	1
LUNG_SCLC	GRIFIN →	+0.135	+5.029	<.001	.006	3	1
LARGE_INTESTINE	OR10K1 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	TRARG1 →	+0.022	+3.345	<.001	.007	3	1
OVARY	TAAR5 →	+0.042	+4.807	<.001	.003	3	1
OVARY	TAAR6 →	+0.801	+4.990	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR14A2 by UBBP4 expression — BREAST

Explore this box plot interactively →