UBAP2

Across TCGA pan-cancer cohorts, UBAP2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UBAP2 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UBAP2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UBAP2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

LUAD, COAD, and LSCC are the cancer types where UBAP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.916	0.279	.001	30	view →
COAD	DFS	Median	All	1.000	0.887	.020	24	view →
LSCC	DFS	Tertile	All	0.395	1.000	.008	8	view →
PDAC	OS	Median	II,III,IV	0.586	0.405	.030	4	view →
CCRCC	DFS	Median	II,III,IV	0.827	0.359	.023	2	view →
UCEC	DFS	Median	All	0.953	0.859	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UBAP2–LUAD (DFS)

Open the LUAD breakdown →