UBAP2

Across TCGA patient cohorts, UBAP2 mutation is significantly associated with the RNA expression of many other genes, with 2,921 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBAP2-associated genes across cancer lineages are SALL4P5, MIR4510, and SAP30. Each is linked with UBAP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBAP2-to-partner and partner-to-UBAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SALL4P5 grouped by UBAP2-low versus UBAP2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBAP2→partner) and Y-score (partner→UBAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SALL4P5 →	+0.032	+3.481	<.001	.008	3	3
CESC	MIR4510 →	+0.195	+4.342	<.001	.007	3	3
UCEC	SAP30 →	+0.397	+2.072	.007	<.001	3	3
READ	GPR6 →	+0.062	+5.039	<.001	.008	3	2
HNSC	OR1L1 →	+0.021	+4.424	.005	.008	3	2
HNSC	RNU2-47P →	+0.313	+4.883	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,921 associations by consensus.

SALL4P5 by UBAP2 expression — LIHC

Explore this box plot interactively →