UBAP2

Across TCGA cell cohorts, UBAP2 mutation is significantly associated with the RNA expression of many other genes, with 478 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBAP2-associated genes across cancer lineages are C20orf85, C8orf34, and VWC2L. Each is linked with UBAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBAP2-to-partner and partner-to-UBAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf85 grouped by UBAP2-low versus UBAP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBAP2→partner) and Y-score (partner→UBAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C20orf85 →	+0.027	+3.969	<.001	.009	3	1
BLOOD_Leukemia	C8orf34 →	+0.090	+4.091	<.001	.002	3	1
BLOOD_Leukemia	VWC2L →	+0.008	+3.339	.002	.006	3	1
BLOOD_Leukemia	PROP1 →	+0.027	+3.289	<.001	.009	3	1
BLOOD_Leukemia	MAGEB18 →	+0.075	+3.567	<.001	.003	3	1
BLOOD_Leukemia	FAM24A →	+0.040	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 478 associations by consensus.

C20orf85 by UBAP2 expression — BLOOD_Leukemia

Explore this box plot interactively →