UBAP1L

Across TCGA patient cohorts, UBAP1L mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBAP1L-associated genes across cancer lineages are MIR4507, YWHAQP7, and MIR6766. Each is linked with UBAP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both UBAP1L-to-partner and partner-to-UBAP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4507 grouped by UBAP1L-low versus UBAP1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBAP1L→partner) and Y-score (partner→UBAP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4507 →	+0.307	+3.420	.004	.005	3	1
UCEC	YWHAQP7 →	+0.117	+2.570	.009	.009	3	1
UCEC	MIR6766 →	+0.355	+3.358	<.001	.006	3	1
COAD	PRR23D2 →	+0.029	+7.741	<.001	.009	3	1
UCEC	RNA5SP379 →	+0.572	+2.577	.002	.009	3	1
UCEC	MIR574 →	+0.482	+3.148	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

MIR4507 by UBAP1L expression — UCEC

Explore this box plot interactively →