UBAP1L

Across TCGA cell cohorts, UBAP1L mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible UBAP1L-associated genes across cancer lineages are OR10K2, OR10T2, and ITGAD. Each is linked with UBAP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both UBAP1L-to-partner and partner-to-UBAP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K2 grouped by UBAP1L-low versus UBAP1L-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBAP1L→partner) and Y-score (partner→UBAP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10K2 →	+0.038	+4.196	<.001	.006	3	1
BREAST	OR10T2 →	+0.110	+4.196	<.001	.006	3	1
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	1
CNS	TAS2R39 →	+0.024	+4.981	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR10K2 by UBAP1L expression — BREAST

Explore this box plot interactively →