UBAP1

Across TCGA cell cohorts, UBAP1 mutation is significantly associated with the mutation status of many other genes, with 3,097 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBAP1-associated genes across cancer lineages are ZNF652, MGAT2, and LACTB. Each is linked with UBAP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBAP1-to-partner and partner-to-UBAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF652 grouped by UBAP1-low versus UBAP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBAP1→partner) and Y-score (partner→UBAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZNF652 →	+6.014	+6.014	.001	.001	1	3
LARGE_INTESTINE	MGAT2 →	+3.459	+3.459	.006	.006	1	3
BLOOD_Lymphoma	LACTB →	+4.429	+5.247	.005	.005	1	3
LARGE_INTESTINE	EFNB2 →	+3.459	+3.459	.006	.006	1	3
BLOOD_Lymphoma	DYRK2 →	+6.014	+6.014	.001	.001	1	3
LARGE_INTESTINE	BZW2 →	+5.044	+4.087	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,097 associations by consensus.

ZNF652 by UBAP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →