Across TCGA pan-cancer cohorts, UBALD2 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated UBALD2 data layer compared with 1 for mutation status and 4 for mass-spec protein.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher UBALD2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBALD2 expression acts as an unfavorable survival marker, although some lineages such as CESC and UVM show a favorable association.
ACC, CESC, and LIHC are the cancer types where UBALD2 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.