Across TCGA pan-cancer cohorts, UBALD1 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of UBALD1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where UBALD1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types UBALD1 is over-expressed in tumor, although a few such as COAD and PDAC show the opposite, repressed pattern.
COAD, PDAC, and CCRCC are the cancer types where UBALD1 tumor–normal differential expression is most reproducible.