UBA7

Across TCGA pan-cancer cohorts, UBA7 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated UBA7 data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher UBA7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBA7 expression acts as an unfavorable survival marker.

COAD, LSCC, and CCRCC are the cancer types where UBA7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.911	1.000	.006	102	view →
LSCC	OS	Tertile	II,III,IV	0.511	0.882	.010	13	view →
CCRCC	DFS	Tertile	IV	0.162	0.887	.038	12	view →
GBM	DFS	Median	All	0.284	0.458	.017	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

UBA7–COAD (DFS)

Open the COAD breakdown →