UBA6

Across TCGA patient cohorts, UBA6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,087 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible UBA6-associated proteins across cancer lineages are COQ8A, PDCD4, and JUNB. Each is linked with UBA6 in more than 4 cancer types. Because this analysis shows association rather than direction, both UBA6-to-partner and partner-to-UBA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBA6 versus COQ8A in BRCA, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBA6→partner) and Y-score (partner→UBA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COQ8A →	-0.490	-0.478	<.001	<.001	3	5
OV	PDCD4 →	-0.527	-0.442	.007	.005	3	5
CCRCC	JUNB →	+0.412	+0.557	<.001	<.001	3	5
COAD	TPI1_S80 →	+0.710	+0.673	<.001	<.001	3	4
BRCA	BCAR1 →	+0.314	+0.612	<.001	<.001	3	4
BRCA	ITGB4 →	+0.455	+0.364	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,087 associations by consensus.

UBA6 vs COQ8A — BRCA

Explore this scatter interactively →