UBA52P8

Across TCGA pan-cancer cohorts, UBA52P8 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated UBA52P8 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher UBA52P8 RNA is associated with better overall survival. In most high-consensus cancer types, elevated UBA52P8 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BRCA show a favorable association.

SKCM, THCA, and LUSC are the cancer types where UBA52P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.401	0.260	<.001	75	view →
THCA	DFS	Tertile	II,III,IV	0.468	0.957	.001	31	view →
LUSC	DFS	Quartile	III,IV	0.506	0.870	<.001	26	view →
KICH	OS	Median	III,IV	0.556	1.000	.010	24	view →
ACC	OS	Median	All	0.722	1.000	.001	22	view →
READ	OS	Median	II,III,IV	0.842	1.000	.005	17	view →
BRCA	DFS	Tertile	III,IV	0.870	0.734	.011	11	view →
LIHC	OS	Tertile	II,III,IV	0.862	0.630	.020	11	view →
UVM	DFS	Median	III,IV	0.207	0.673	.009	9	view →
LGG	DFS	Median	All	0.791	0.869	.008	9	view →
MESO	OS	Quartile	III,IV	0.503	0.717	.019	8	view →
HNSC	DFS	Quartile	All	0.223	0.553	.020	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

UBA52P8–SKCM (OS)

Open the SKCM breakdown →