UBA52P3

Across TCGA pan-cancer cohorts, UBA52P3 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated UBA52P3 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher UBA52P3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated UBA52P3 expression acts as an unfavorable survival marker, although some lineages such as CESC and SKCM show a favorable association.

CESC, KIRP, and HNSC are the cancer types where UBA52P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.848	0.658	.001	50	view →
KIRP	OS	Tertile	All	0.878	0.983	.001	40	view →
HNSC	DFS	Median	II,III,IV	0.222	0.568	<.001	38	view →
ACC	OS	Tertile	All	0.613	1.000	.002	35	view →
SKCM	OS	Quartile	All	0.592	0.285	.002	29	view →
PAAD	OS	Tertile	II,III,IV	0.510	0.680	.018	12	view →
READ	OS	Median	IV	0.520	1.000	.011	12	view →
LIHC	OS	Tertile	II,III,IV	0.894	0.585	.009	9	view →
THCA	DFS	Median	IV	0.602	0.931	.019	7	view →
THYM	DFS	Tertile	All	1.000	0.778	.013	6	view →
MESO	OS	Tertile	III,IV	0.285	0.507	.025	6	view →
KICH	DFS	Median	All	0.734	0.939	.023	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

UBA52P3–CESC (DFS)

Open the CESC breakdown →