Across TCGA pan-cancer cohorts, UBA52 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UBA52 data layer compared with 18 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher UBA52 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBA52 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

GBM, CCRCC, and COAD are the cancer types where UBA52 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Median	All	0.283	0.451	.004	11	view →
CCRCC	OS	Median	All	0.647	1.000	.005	7	view →
COAD	DFS	Median	IV	1.000	0.605	.043	6	view →
PDAC	DFS	Quartile	All	0.335	0.595	.032	6	view →
HNSC	OS	Quartile	All	1.000	0.948	.041	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: UBA52 tumor-vs-normal RNA expression · all UBA52 data types