Across TCGA patient cohorts, UBA52 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBA52-associated genes across cancer lineages are MIR4773-1, SUMO2P18, and IGLVVI-25-1. Each is linked with UBA52 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBA52-to-partner and partner-to-UBA52 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBA52→partner) and Y-score (partner→UBA52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR4773-1 →	+0.287	+5.307	<.001	.001	3	2
BLCA	SUMO2P18 →	+0.186	+4.975	.002	<.001	3	1
BLCA	IGLVVI-25-1 →	+0.083	+5.040	<.001	.002	3	1
BLCA	MTRNR2L7 →	+0.048	+4.857	.004	<.001	3	1
BLCA	MIR6892 →	+0.176	+5.632	<.001	.001	3	1
BLCA	SCGB1D4 →	+0.066	+4.497	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

UBA52 survival (RNA) · tumor vs normal (RNA) · all UBA52 data types