UBA3

Across TCGA cell cohorts, UBA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,041 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UBA3-associated GO terms across cancer lineages are Spindle assembly, Regulation of cytokinesis, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with UBA3 in more than 12 cancer types. Because this analysis shows association rather than direction, both UBA3-to-partner and partner-to-UBA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle assembly grouped by UBA3-low versus UBA3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBA3→partner) and Y-score (partner→UBA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Spindle assembly →	+0.084	+0.768	<.001	<.001	3	13
KIDNEY	Regulation of cytokinesis →	+0.070	+0.800	<.001	<.001	3	12
LIVER	Regulation of metaphase/anaphase transition of cell cycle →	+0.097	+0.553	.002	.004	2	12
URINARY_TRACT	Regulation of sister chromatid segregation →	+0.111	+0.681	.002	.001	2	12
LUNG_NSCLC_LUSC	Regulation of L-glutamate import across plasma membrane →	+0.231	+0.732	<.001	.004	3	11
LIVER	Microtubule cytoskeleton organization involved in mitosis →	+0.072	+0.599	.006	.007	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,041 associations by consensus.

Spindle assembly by UBA3 expression — OVARY

Explore this box plot interactively →