UBA2

Across TCGA cell cohorts, UBA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,649 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UBA2-associated GO terms across cancer lineages are Mitotic sister chromatid cohesion, DNA-templated DNA replication, and Interstrand cross-link repair. Each is linked with UBA2 in more than 16 cancer types. Because this analysis shows association rather than direction, both UBA2-to-partner and partner-to-UBA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic sister chromatid cohesion grouped by UBA2-low versus UBA2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBA2→partner) and Y-score (partner→UBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitotic sister chromatid cohesion →	+0.119	+0.858	<.001	<.001	3	17
KIDNEY	DNA-templated DNA replication →	+0.092	+0.663	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.078	+0.955	.004	<.001	3	17
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.207	+0.737	<.001	<.001	3	16
KIDNEY	Sister chromatid cohesion →	+0.104	+0.742	<.001	<.001	3	15
URINARY_TRACT	Regulation of chromosome segregation →	+0.101	+0.877	.001	.004	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,649 associations by consensus.

Mitotic sister chromatid cohesion by UBA2 expression — BREAST

Explore this box plot interactively →