U2AF1L5

Across TCGA patient cohorts, U2AF1L5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,131 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible U2AF1L5-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Maintenance of cell number, and Regulation of peptidyl-lysine acetylation. Each is linked with U2AF1L5 in more than 23 cancer types. Because this analysis shows association rather than direction, both U2AF1L5-to-partner and partner-to-U2AF1L5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by U2AF1L5-low versus U2AF1L5-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (U2AF1L5→partner) and Y-score (partner→U2AF1L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Negative regulation of gene expression, epigenetic →	+0.033	+0.272	<.001	<.001	3	24
THYM	Maintenance of cell number →	+0.033	+0.256	<.001	<.001	3	22
GBM	Regulation of peptidyl-lysine acetylation →	+0.037	+0.230	<.001	<.001	3	21
GBM	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.043	+0.169	<.001	<.001	3	21
THYM	Peptidyl-lysine acetylation →	+0.031	+0.254	.003	<.001	3	21
ESCA	Negative regulation of RNA splicing →	+0.039	+0.263	<.001	<.001	1	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,131 associations by consensus.

Negative regulation of gene expression, epigenetic by U2AF1L5 expression — GBM

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