U2AF1L5

Across TCGA cell cohorts, U2AF1L5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,746 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible U2AF1L5-associated GO terms across cancer lineages are Cell cycle DNA replication, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Double-strand break repair via break-induced replication. Each is linked with U2AF1L5 in more than 12 cancer types. Because this analysis shows association rather than direction, both U2AF1L5-to-partner and partner-to-U2AF1L5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell cycle DNA replication grouped by U2AF1L5-low versus U2AF1L5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (U2AF1L5→partner) and Y-score (partner→U2AF1L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cell cycle DNA replication →	+0.162	+0.749	.001	.007	3	13
URINARY_TRACT	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.108	+0.881	<.001	<.001	3	13
BONE	Double-strand break repair via break-induced replication →	+0.262	+1.004	.003	.004	3	13
BONE	Nuclear DNA replication →	+0.201	+0.995	.002	.002	3	12
BONE	DNA replication-dependent chromatin assembly →	+0.184	+0.960	.005	.005	2	13
SOFT_TISSUE	Negative regulation of translational elongation →	+0.136	+0.727	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,746 associations by consensus.

Cell cycle DNA replication by U2AF1L5 expression — BONE

Explore this box plot interactively →