U2AF1L4

Across TCGA patient cohorts, U2AF1L4 mutation is significantly associated with the RNA expression of many other genes, with 292 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible U2AF1L4-associated genes across cancer lineages are MTCO2P7, MIR7702, and MTND6P14. Each is linked with U2AF1L4 in more than 2 cancer types. Because this analysis shows association rather than direction, both U2AF1L4-to-partner and partner-to-U2AF1L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCO2P7 grouped by U2AF1L4-low versus U2AF1L4-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (U2AF1L4→partner) and Y-score (partner→U2AF1L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MTCO2P7 →	+0.151	+5.788	<.001	.003	3	3
UCEC	MIR7702 →	+0.284	+4.601	<.001	.003	3	2
SKCM	MTND6P14 →	+0.034	+4.671	<.001	.004	3	2
SKCM	RN7SL173P →	+0.301	+3.508	<.001	.006	3	2
BRCA	RNU6-102P →	+0.279	+9.057	<.001	.003	3	2
LUSC	MIR1271 →	+0.619	+4.187	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 292 associations by consensus.

MTCO2P7 by U2AF1L4 expression — BLCA

Explore this box plot interactively →