U2AF1L4

Across TCGA patient cohorts, U2AF1L4 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible U2AF1L4-associated genes across cancer lineages are CD8+ naive T-cells, naive B-cells, and Epithelial cells. Each is linked with U2AF1L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both U2AF1L4-to-partner and partner-to-U2AF1L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by U2AF1L4-low versus U2AF1L4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (U2AF1L4→partner) and Y-score (partner→U2AF1L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.033	+3.016	.012	.019	3	2
COAD	naive B-cells →	+0.010	+3.366	.046	.040	3	1
UCEC	Epithelial cells →	-0.084	-2.459	.015	.020	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ naive T-cells by U2AF1L4 expression — UCEC

Explore this box plot interactively →