TYW3

Across TCGA patient cohorts, TYW3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,001 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TYW3-associated proteins across cancer lineages are NFIA, SEC24A, and NELFB. Each is linked with TYW3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TYW3-to-partner and partner-to-TYW3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYW3 versus NFIA in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW3→partner) and Y-score (partner→TYW3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NFIA →	+0.390	+0.425	<.001	<.001	3	5
LSCC	SEC24A →	-0.277	-0.337	<.001	<.001	3	5
GBM	NELFB →	+0.248	+0.247	.005	.003	3	4
COAD	ARFGEF2 →	-0.189	-0.497	<.001	<.001	3	4
COAD	NCOR1 →	+0.243	+0.544	<.001	<.001	3	4
CCRCC	PRDX4 →	-0.353	-0.325	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,001 associations by consensus.

TYW3 vs NFIA — BRCA

Explore this scatter interactively →