TYW3

Across TCGA patient cohorts, TYW3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,583 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TYW3-associated genes across cancer lineages are SEMA4D, ADRA2A, and RBM43. Each is linked with TYW3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TYW3-to-partner and partner-to-TYW3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TYW3 versus SEMA4D in GBM, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW3→partner) and Y-score (partner→TYW3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEMA4D →	-0.585	-0.259	.004	.001	3	3
OV	ADRA2A →	-1.534	-0.769	<.001	<.001	3	3
CCRCC	RBM43 →	-0.615	-0.354	<.001	<.001	3	3
LUAD	ZNF441 →	-0.417	-0.242	.002	.001	3	3
LSCC	YPEL2 →	-0.458	-0.286	<.001	<.001	3	2
UCEC	BAK1P1 →	-0.487	-0.219	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,583 associations by consensus.

TYW3 vs SEMA4D — GBM

Explore this scatter interactively →