TYW3

Across TCGA cell cohorts, TYW3 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,068 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TYW3-associated GO terms across cancer lineages are Cellular response to toxic substance, Mesenchyme migration, and Positive regulation of cellular senescence. Each is linked with TYW3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TYW3-to-partner and partner-to-TYW3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to toxic substance grouped by TYW3-low versus TYW3-high in SKIN.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW3→partner) and Y-score (partner→TYW3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cellular response to toxic substance →	+0.056	+1.156	.001	.003	3	3
BLOOD_Lymphoma	Mesenchyme migration →	+1.902	+4.255	.003	.005	3	3
BLOOD_Lymphoma	Positive regulation of cellular senescence →	-0.186	-4.270	.004	.005	3	3
OESOPHAGUS	Positive regulation of cyclin-dependent protein kinase activity →	+0.171	+2.409	.007	.001	3	3
OESOPHAGUS	Endoplasmic reticulum tubular network membrane organization →	-0.209	-2.181	<.001	.008	3	3
BLOOD_Leukemia	Telomere maintenance in response to DNA damage →	-0.119	-2.282	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,068 associations by consensus.

Cellular response to toxic substance by TYW3 expression — SKIN

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