TYW1B

Across TCGA cell cohorts, TYW1B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,979 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TYW1B-associated GO terms across cancer lineages are Mitotic DNA integrity checkpoint signaling, Wybutosine biosynthetic process, and RNA export from nucleus. Each is linked with TYW1B in more than 8 cancer types. Because this analysis shows association rather than direction, both TYW1B-to-partner and partner-to-TYW1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA integrity checkpoint signaling grouped by TYW1B-low versus TYW1B-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TYW1B→partner) and Y-score (partner→TYW1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Mitotic DNA integrity checkpoint signaling →	+0.061	+0.577	<.001	.001	3	9
STOMACH	Wybutosine biosynthetic process →	+0.105	+1.487	<.001	<.001	2	9
PANCREAS	RNA export from nucleus →	+0.088	+0.994	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of DNA repair →	+0.023	+0.367	.005	.004	3	7
BLOOD_Leukemia	Positive regulation of cell cycle process →	+0.052	+0.520	<.001	.005	3	7
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.066	+0.986	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,979 associations by consensus.

Mitotic DNA integrity checkpoint signaling by TYW1B expression — BLOOD_Leukemia

Explore this box plot interactively →